Answer:
The vitamin D receptor (VDR) is present in mammary gland, and VDR ablation is associated with accelerated glandular development during puberty. VDR is a nuclear receptor whose ligand, 1,25-dihydroxyvitamin D [1,25-(OH)(2)D] is generated after metabolic activation of vitamin D by specific vitamin D hydroxylases. In these studies, we demonstrate that both the VDR and the vitamin D 1-alpha hydroxylase (CYP27B1), which produces 1,25-(OH)(2)D are present in mammary gland and dynamically regulated during pregnancy, lactation, and involution. Furthermore, we show that mice lacking VDR exhibit accelerated lobuloalveolar development and premature casein expression during pregnancy and delayed postlactational involution compared with mice with functional VDR. The delay in mammary gland regression after weaning of VDR knockout mice is associated with impaired apoptosis as demonstrated by reductions in terminal deoxynucleotidyl transferase-mediated deoxyuridine nick-end labeling staining, caspase-3 activation and Bax induction. Under the conditions used in this study, VDR ablation was not associated with hypocalcemia, suggesting that altered mammary gland development in the absence of the VDR is not related to disturbances in calcium homeostasis. Furthermore, in the setting of normocalcemia, VDR ablation does not affect milk protein or calcium content. These studies suggest that the VDR contributes to mammary cell turnover during the reproductive cycle, and its effects may be mediated via both endocrine and autocrine signaling pathways. Unlike many mammary regulatory factors that exert transient, stage-specific effects, VDR signaling impacts on mammary gland biology during all phases of the reproductive cycle.
Explanation:
i-summarize niyo nalang po
When passing, _____ only when you can see the tires of the vehicle you passed in your rearview mirror.
Which of the following statements about the administration of cpr is true?.
Explanation:
hope this will helps you
Rocky point brewery (rpb) plans to file an initial public offering (ipo) in june 20x3. Olsen & alain, cpas (o&a) has performed calendar year end audits of rpb since 20x0 and also helps rpb prepare monthly financial statements in accordance with aicpa independence rules. O&a terminated the accounting services in december 20x2. Under sec independence rules, could rpb continue to engage o&a as its auditor when it files its ipo?.
Based on the information given about the public offering, the correct option is C. No, because the prohibited non-audit services were performed during the period covered by the financial statements.
From the complete information, it was stated that Rocky point brewery plans to file an initial public offering in June 20x3 while Olsen & Alain, cpas has performed calendar year-end audits of rpb since 20x0.
Under the security exchange commission and PCAOB, it should be noted that Rocky point brewery cannot engage O & A to be their auditors now that's it's a public company.
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How long does the earth take to complete its rotation brainly.
Answer:
since the earth completes on rotation in about 24 hours.
Which graph below would match the situation described? a car travelling at 23 mi/h accelerates to 45 mi/h in 5 seconds. It maintains that speed for the next 5 seconds, and then slows to a stop during the next 5 seconds.
If a car travels at 23 mi/h accelerates to 45 mi/h in 5seconds, the acceleration of the car is expressed as:
a = v-u/t
u is the initial velocitya is the accelerationt is the timea = 45-23/0.001388
a = 15,850.14mi/hr²
For the graph, the initial velocity will be 23mi/hr. The body will maintain a constant velocity for 5 seconds before decelerating for 5 secs. The required graph is as shown:
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You have 41. 6 g of o2 gas in a container with twice the volume as one with co2 gas. The pressure and temperature of both containers are the same. Calculate the mass of carbon dioxide gas you have in the container.
Answer: The mass of carbon dioxide is 28.6 grams
Explanation: Step 1: Data given
Mass of O2 = 41.6 grams
Volume of the O2 container = 2V
Volume of the CO2 container = V
Pressure and temperature are the same
Step 2: Ideal gas law
The ideal gas law = p*V=nRT
For O2: p*2V = n(O2)*R*T
For CO2: p*V = n(CO2)*R*T
n(O2)*R*T / P*2V = n(CO2)*R*T / P*V
Since P, R and T are contstant, we can simplify this to:
n(O2)/2 = n(CO2)
Step 3: Calculate moles of O2
Moles O2 = mass O2/ Molar mass O2
Moles O2 = 41.6 grams / 32 g/mol
Moles O2 = 1.3 mol O2
The number of moles CO2 = 0.65 mol
Mass of CO2 = Moles CO2 * Molar Mass CO2
Mass of CO2 = 0.65 mol * 44.01 g/mol
Mass of CO2 = 28.6 grams
The mass of carbon dioxide is 28.6 grams
mark me as brainliest because it took me hour to solve this pls
there are 4 factors in the personal safety protocols
Answer:
A. Knowledge and awareness: Knowing how to recognize that an environment has dangers that must be avoided
B Ability: Be realistic in telling a co-worker that his or her ability is not sufficient to promote safe work. Example: an employee prevents a trainee from working with acids, since the trainee does not have enough capacity to handle these elements safely.
C. State of Mind: Professionals must always be aware that all team members are in emotional and psychological conditions of sufficient quality to carry out work safely. Example: a truck driver who received sad news over the phone, decides to park the truck and only drive again when he is in a better state of mind.
D. Environmental conditions: Analyze possible environmental hazards and avoid them. Example: electricians, avoid manipulating power cords in stern environments in moments of rain, as there is a risk of electroshock.
Explanation:
Iq is determined by brainly.
Answer:
False
Explanation:
Intelligence Quotient (IQ) is a number representing a person's reasoning ability. It's determined by dividing a person's score on a special test by his or her age, then multiplying by 100
Answer:
false
Explanation:
have a good night :)
With the use/abuse of alcohol the heart is less efficient.
Answer:
Explanation:
because it is overloading the heart with a non regular item.
Find the solution to the system of equations. You can use the interactive graph below to find the solution. \begin{cases} -3x-9y=18 \\\\ 4x+3y=12 \end{cases} ⎩ ⎪ ⎪ ⎨ ⎪ ⎪ ⎧ −3x−9y=18 4x+3y=12 .
The solution to the system of equations is x = 30 and y = -36.
The two equations are known as simultaneous equations. The elimination method would be used to determine to find the solutions.
−3x−9y=18 equation 1
4x+3y=12 equation 2
In order to determine the value of x, take the following steps;
Multiply equation 2 by 3
12x + 9y = 36 equation 2
Add equation 1 and equation 2
x = 30
Substitute for x in equation 2
4(30) + 3y = 12
120 + 3y = 12
120 - 12 = -3y
108 = -3y
y = 108 / -3 = -36
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Answer:
x=6
y=-4
Explanation:
got it on khan <3
Put the plot events from animal farm in the correct order.
Answer:
how can u put more detail please
A rectangular plot of land is 0. 4 kilometer long and 0. 07 kilometer wide. What is its area in square kilometers?.
We are given –
Length of rectangular is = 0.4 kmBreadth of rectangular = 0.07 kmWe are asked to find out the are in square kilometers. As we know –
Area of rectangular plot = Length × Breadth
Area of rectangular plot = 0.4 km × 0.07km
Area of rectangular plot = 0.028 square km
Henceforth, are of rectangular plot is 0.028 square km.________________________________
X + y = 12 x - y = 10 what is the value of the x-determinant for the system shown?.
Which of the following best describes the long-term impact of using a renewable energy source?.
biomass releases great house gasses when burned and this is a long term impact of a renewable energy source.
Zen gardens were the result of intense __________ and manual _________.
Zen gardens were the result of intense MEDITATION and manual LABOR. These gardens are known as Japanese rock gardens.
The Japanese rock gardens (also known as Zen gardens) were developed by Buddhist monks to aid in meditation.
The Zen gardens represent one of the most important characteristics of Japanese culture.
These Japanese rock gardens use sand and rocks in order as a manner to highlight and celebrate life.
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Answer: Zen gardens were the result of intense MEDITATION and manual LABOR. These gardens are known as Japanese rock gardens. The Japanese rock gardens (also known as Zen gardens) were developed by Buddhist monks to aid in meditation. The Zen gardens represent one of the most important characteristics of Japanese culture. These Japanese rock gardens use sand and rocks in order as a manner to highlight and celebrate life.
Explanation:
art history 23 edge.
Which of the following statements about writing introductions and conclusions is true.
Answer:
✓ Always write the introduction first and the conclusion last is a statem…
Explanation:
Mi padre y yo 1 of 2 (quitar) las cortinas y 2 of 2 (limpiar) las ventanas.
For the sentence to be grammatically correct, the verbs must be conjugated in the preterite tense as follows:
Mi padre y yo quitamos las cortinas y limpiamos las ventanas. Translation: My father and I removed the curtains and cleaned the windows.The preterite tense is a verb tense that is used to describe actions that occurred prior to the moment of enunciation.
The sentence "Mi padre y yo quitamos las cortinas y limpiamos las ventanas", describes actions performed in the past.
Therefore, we can conclude that the preterite tense is a verb tense that states an action that occurred in the past.
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A human fingernail has a hardness of approximately 2. 5. Which two minerals are softer than a human fingernail?.
Answer:
gypsum and talc
Explanation:
gypsum has 2 hardness and talc has 1
Explain one example of why nationalism thrived in the period c. 1750-c. 1900.
Nationalism flourished between 1750 and 1900 because during this time nations were establishing and strengthening themselves internally as homogeneous groups with a common culture.
What is nationalism?Nationalism is a term to refer to a sociopolitical ideology that emerged together with the modern concept of the nation that characterized different historical events such as:
Age of the Revolutions.Independence movements of the European colonies in America.Nationalism is based on a higher level of awareness and identification with the reality and history of a nation, that is, it is based on the belief that there are certain characteristics common to a national community that must be legitimized and politically modeled.
This ideology was very successful from the middle of the 18th century because from that time there was a transition between the kingdoms and the Middle Ages to the modern age and the conformation of the modern states.
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Answer:
Nationalism thrived in 1750-1900 because during that period people began to realize nationalist aspirations. The French revolution inspired people all over Europe, the revolution spread ideas of liberty, equality, fraternity, and the overall spirit of nationalism.
Cold duck airlines flies between tacoma and portland.
Answer:
continue flying until the lease expires and then drop the run.
Explanation:
a player pays $15 to play a game in which a chip is randomly selected from a bag of chips. the bag contains 10 red chips, 4 blue chips, and 6 yellow chips. the player wins $5 if a red chip is selected, $10 if a blue chip is selected, and $20 if a yellow chip is selected. let the random variable x represent the amount won from the selection of the chip, and let the random variable w represent the total amount won, where w=x−15. what is the mean of w ?
The mean of w which represents the total amount won where w = x + 15 is;
w = -$4.5
We are given;
Winnings if a red chip is selected; x₁ = $5.
Now, there are 10 red chips in a bag of 20 chips.
Thus, the probability of this outcome is:
p₁ = 10/20
p₁ = 1/2
Winnings if a blue chip is selected; x₂ = $10
Now, there are 4 blue chips in a bag of 20 chips.
Thus, the probability of this outcome is:
p₂ = 4/20
p₂ = 1/5
Winnings if a yellow chip is selected; x₃ = $20
Now, there are 6 blue chips in a bag of 20 chips.
Thus, the probability of this outcome is:
p₃ = 6/20
p₃ = 3/10
Finally, the expected value is:
E(X) = 5(¹/₂) + 10(¹/₅) + 20(³/₁₀)
E(X) = $10.5
We are told that w = x - 15
where x is the amount won from selection of chip which is E(X) = $10.5
Thus;
w = 10.5 - 15
w = -$4.5
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The more you drive:
The less likely you are to have a collison because you are getting more practice
The more likely you are to have a collision because you are exposed to more chances for trouble
Doesn't make any difference in how likely you are to have a collision because it only takes one mistake
Doesn't make any difference in how likely you are to have a collision because it could be someone else's fault
The more you drive , the less likely you are to have a collision because you
are getting more practice.
We should note that practice makes perfection means that collision will
occur mainly if other people at fault. When we aren't perfect in driving then
the collision could also be from us which increases our chances of having a
collision.
This is the main reason why driving more will make collision less likely and
makes option A the most appropriate choice.
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Which r–value represents the strongest negative correlation? –0. 7 –0. 22 0. 38 0. 9.
Answer:
2
Explanation:
Because if you add 1 to 8 you get 9 then subtract 9 by 7 then and your answer is 2
Which of the following is an example of a job surplus.
Answer:
The demand for roofers is higher than the number off people willing to do roofing
An example of a job surplus is the demand for roofers is higher than the number of people willing to do roofing. Option A
How to determine the exampleA job surplus refers to a situation in the job market where there are more available workers or job seekers than there are job openings or positions available. In other words, it's a condition where the supply of labor exceeds the demand for it in a particular field or industry.
'The demand for roofers is higher than the number of people willing to do roofing', illustrates a scenario of job surplus. This means that there are more roofing job opportunities available than there are individuals who are willing to take up the job of being a roofer.
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The complete question:
Which of the following is an example of a job surplus? (1 point)
The demand for roofers is higher than the number of people willing to do roofing.**
Roofers demand more pay for the work they are doing.
The number of roofers is higher than the roofing jobs available.
There are more roofing materials being manufactured than there are houses that need them.
A measure of the average value of a random variable is called.
Answer:
The mean can be regarded as a measure of `central location' of a random variable. It is the weighted average of the values that X can take, with weights provided by the probability distribution. The mean is also sometimes called the expected value or expectation of X and denoted by E(X).
Sqrt is a parallelogram. If m∠qst = 72°, which of the following statements is true? m∠sqr = 72° m∠qrt = 72° m∠qsr = 36° m∠trq = 108°.
The statement that is true for parallelogram sqrt with m∠qst = 72° is that m∠qrt = 72°.
Sqrt is a parallelogram.
Parallelograms are quadrilaterals that have both pairs of opposite sides parallel.
parallelograms has both sides congruent to each other.
Parallelograms opposite angles are equal.
Consecutive angles are supplementary in a parallelogram
Therefore, If m∠qst = 72° then m∠qrt = 72°.
This follows the rules that opposite angles are congruent in a parallelogram.
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I can confirm it is QRT = 72.
I got it right on the test
What does this excerpt from the poem describe? a thought-provoking walk at night a ring of street lights surrounding a park a lunar eclipse a party held at midnight.
The excerpt given above from a poem can be said to be about a thought-provoking walk at night.
The speaker:
Makes reference to street lamps, lunar incantations, and how it is midnight. Talks about how their memory is being shaken. Makes reference to how they are passing objects. Deducing the meaningThe fact that it is midnight means that this is night and the reference to the passing objects means the speaker is walking. The speaker also talks about the impact this is having on their memory.
We can therefore conclude that this is about a thought-provoking walk at night.
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Answer:
the answer is A)
Explanation:
Which of the following goods would be included in the calculation of gross domestic product? select the two correct answers.
Answer:
We need a picture?? There is no picture.
Decide if por or para should be used in the following sentence. Ella es muy extrovertida _____ una chica tímida. Por para.
The correct option is Ella es muy extrovertida para una chica tímida.
Por and para are two Spanish prepositions, but they are used differently.
When to use por?
We use por when we talk about
Why something happened To mention who did something. For example, la comida fue hecha por el John.When do we use para?
We use para when:
We want to talk about the what.We are using adjectives to talk about someone or something and making comparisons.
In conclusion, as the sentence is talking about the characteristics of a girl and making a comparison, the correct word is para.
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Answer:
para
Explanation:
Complete the table by dragging the correct sequence or formula to the correct container.
There are a lot of functions in mathematics. The answers are:
Arithmetic are: 3, 8, 13, 18,... , 4, 8, 12, 16,...Geometric are : 4, 8, 12, 16,... , 2,6, 18, 54,...Neither Arithmetic nor Geometric are: 5, 10, 20, 30,...Arithmetic sequenceAn arithmetic sequence is known to be a type of sequence that progresses through addition while a geometric sequence is one that progresses upward by multiplication.
3, 8, 13, 18.. is an addition so it is arithmetic sequence because you have to add 5 constantly to find the next term.
5, 10, 20, 40,... is multiplication and so it is geometric because you multiply the previous term by a factor of 2 each time to find the next term of the sequence.
5, 10, 20, 30,... is neither both as it does not follow the ways set by the rules of geometric or arithmetic sequences.
See full question below
Drag each sequence to the correct location on the table.
Consider the given sequences. Place each sequence in the appropriate column in the table
3, 8, 13, 18,..
5, 10, 20, 40,...
2,6, 18, 54,...
5, 10, 20, 30,...
4, 8, 12, 16,...
Arithmetic
Geometric
Neither Arithmetic nor Geometric
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