prostate cells usually require testosterone and other androgens to survive. but some prostate cancer cells thrive despite treatments that eliminate androgens. one hypothesis is that estrogen, often considered a female, may be activating genes normally controlled by an androgen in these cancer cells. desribe one or more experiments to test this hypothesis

Answers

Answer 1

One can check for the translation and transcription of genes of interest in the absence of androgens, one can check whether the estrogen is involved in the expression of oncogenic proteins of interest by depleting the estrogen, and one can also examine the existence of estrogen receptor complex in the prostrate cancer cells nuclei.  

• One can check for the translation and transcription of genes of interest in the non-existence of androgens and if these genes are expressed then this suggests that apart from androgens other factors also affect their expression.  

• One can deplete the estrogen from cancer cells and if the involvement of estrogen is there in the expression of oncogenic proteins of interest then its reduction will result in diminished multiplication rates in cancer cells.  

• One can also test the existence of estrogen-receptor complex in the prostate cancer cells nuclei to confirm that estrogen is taking part in the regulation of gene expression.  

Thus, various experiments can be conducted to check that whether the expression of genes controlled by the androgens under normal conditions are affected by the presence of estrogens in prostate cancer cells.  

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Related Questions

In this type of passive transport, materials may have their movements helped by membrane proteins.
Facilitated diffusion
Simple diffusion
Simple diffusion
Exocytosis

Answers

Answer:

Facilitated diffusion

Explanation:

Diffusion across a membrane, along a concentration gradient via membrane protiens. No energy is required hence passive.

NAD+ is a limiting factor in glycolysis. In the absence of ____________________ the conversion of (1) ____________________ to NAD+ via the ______________________________ is prevented from happening.

Answers

In the absence of ADP, the conversion of NADH to NAD+ via the electron transport chain is prevented from happening.

What is glycolysis?

Glycolysis is the series of reactions by which glucose is broken down to pyruvate by the body.

NAD+ is a limiting factor in glycolysis. In the absence of ADP, the conversion of NADH to NAD+ via the electron transport chain is prevented from happening.

In conclusion, NAD+ is a limiting factor in glycolysis.

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During and after photosynthesis, energy changes from one form to another in a series of steps. Which step related to this energy transformation occurs second?

Answers

The step that relates to the energy transformation in photosynthesis is respiration.

What is respiration?

Respiration is the process whereby the chemical energy locked up in carbohydrates is unlocked into another energy form that is usable to living organisms.

In other words, chemical energy in carbohydrates is converted to ATP. This process can take place with (aerobic respiration) or without (anaerobic respiration) oxygen.

Carbohydrates are primarily generated from photosynthesis by green plants.

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Need help on this question

Answers

Answer:

the answer is D which is CJD

what is this a picture of

watershed
wetland
sinkhole

Answers

Answer:

it's a watershed

Explanation:

basically it's a channel that drains/carries runoff to a common point like the lake in the picture. water, sediment, and other materials are carried by the river to the lake.

What is thWhich is a structure that directs the cell's activities?e basic unit of structure and function of all living organisms?

Answers

The nucleus is the  structure that directs the cell's activities of living organisms.

What is Nucleus?

This is an organelle which is usually membrane bound and contains the chromosomes.

It is involved in the control of the synthesis of proteins thereby aiding the directing of the cell activities.

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The lens of a person's eye becomes thinner as the person watches a train leave. This is an example of _________________________.

Answers

Answer:

Refraction

Explanation:

The lens is pulled thin, allowing the light rays to refract slightly.

True or false? Mendel's inheritance laws hold true for all types of inheritance in humans.
O True
O False

Answers

Answer:False

Explanation:

Mendel' s law of independent assortment does not hold true for the genes that are located closely on. A. Same chromosome. B. Non-homologous chromosomes.

which one of the following are primary lymphoid organ?

i) Bone marrow and spleen
ii) spleen and thymus​

Answers

Answer:

The options are not complete because the answer is neither i or ii

spleen is a secondary lymphoid organ

the correct answer is Bone marrow and thymus

What country often experiences the first and worst effects of El Nino, including flooding and destruction of villages?
A. India
B. Japan
C. United States
D. Peru

Answers

Peru is the country that often experiences the first and worst effects of El Nino, including severe flooding.

El Nino is a climatic pattern which describes the unusual warming of surface waters and it is part of a larger phenomenon called 'El Nino - southern oscillation (ENSO)'.

ENSO includes the El Nino and La Nino, the warm phase and cool phase respectively. El Nino occurs irregularly at two - seventy years intervals.

El Nino events are indicated by the increase in sea surface temperature by 0.9 Fahrenheit for at least five successive three months intervals.

El Nino has devastating impacts on the Peruvian and Ecuadorian economies. They cause an increase in precipitation which results in a drastically increased rainfall contributing to coastal flooding and erosion. It also destroys buildings, crops and limits transportation.  

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PLEASE ANSWER QUICK
What is the renewability of geothermal power?

It is a nonrenewable energy source.
It is an unlimited, clean energy source.
It can be replenished by splitting nuclei.
It can use the same fuel cells repeatedly.

Answers

The answer is the 2nd option!

The formation of the many kinds of body cells that make up an embryo begins with

Answers

The formation of multicellular organisms commences with a single-celled zygote, which divides rapidly to form the blastula. Cleavage refers to the rapid, multiple shots of cell division.

What is an embryo?

Following conception, the baby enters the embryonic stage, a period of radical shift.

This stage lasts from the fifth to the tenth week of pregnancy. During a certain stage, the baby is referred to as an embryo. Several changes take place even during embryonic stage.

The primary distinction between an egg and an embryo is that an embryo is formed after the gametes are fertilized, whereas an egg is extracted from the ovary and stored in a freezer prior to fertilization.

Thus, multicellular organisms begin with a single-celled zygote that divides speedily to form the blastula. Cleavage is a term that refers to rapid, multiple strikes of cell division.

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Answer:2

Explanation:because lk

How We can educate people from the ecological footprint that the 3 main factors of the footprint are transportation, housing and food decisions?

Answers

When considering educating people from the ecological perspective, it is important to remark eco-friendly methods of transportation, sustainable homes, and avoid wasting food.

How education is associated with an ecological perspective?

The process of education should ideally exhibit a deep connection with ecological issues in order to preserve natural resources and achieve successful resource management.

For example, transportation may be based on the use of eco-friendly strategies such as cycling and the development of suitable green roads.

In conclusion, when considering educating people from the ecological perspective, it is important to remark eco-friendly methods of transportation, sustainable homes, and avoid wasting food.

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Classify the following organisms as eubacteria, archebacteria, protists, fungi or other
A. Eubacteria coli
B. Plasmodium
C giardia lamblia
D. adenovirus
E. Methanogens
F. Lichen
G. Yeast

Answers

The correct class of the following organisms is as follows:

Eubacteria -:E coliProtist- PlasmodiumProtist- Giardia lambliaOther- adenovirus Archaebacteria - MethanogensFungi - LichenFungi- yeast

What is a domain in biology?

Domain refers to the highest rank in the classification of organisms, above kingdom.

The three-domain system are as follows:

EubacteriaArchaeaEukaryota

The correct class of the following organisms is as follows:

Eubacteria -:E coliProtist- PlasmodiumProtist- Giardia lambliaOther- adenovirus Archaebacteria - MethanogensFungi - LichenFungi- yeast

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A tonicity with a high concentration of solutes is said to be _________. hypertonic isotonic selectively permeable hypotonic

Answers

Answer:

Hypertonic

Explanation:

A tonicity with a high concentration of solutes is said to be Hypertonic.    

I hope it helps! Have a great day!

Pan~

Tonicity with a high concentration of solutes is said to be hypertonic.

Tonicity is the ability of an extracellular solution to allow the movement of water in and out of the cell by osmosis. The terms hypertonic, isotonic and hypotonic decide the movement of water into or out of the cell.

The hypertonic solution is a kind of solution which has a high concentration of solutes (salts, electrolytes). In Biology, a cell is said to be in a hypertonic solution if the outside solution has a high concentration of solutes than the inside the cytoplasm of the cell. In this situation, there will be a net flow of water out of the cell.

The hypotonic solution is a type of solution which has a low concentration of solute. ). In Biology, a cell is said to be in a hypotonic solution if the outside solution has less concentration of solutes than the inside the cytoplasm of the cell. In this situation, there will be a net flow of water into the cell.

Isotonic solution is one which has the same concentration of water and solutes as inside the cytoplasm of a cell. If a cell is placed in an isotonic solution, there is no net water movement.

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20 POINTS - AP Biology

In a certain population of rats....

Answers

The predicated frequency of homozygous dominant rats at are: 0.11 (Option A). See the explanation below.

What is a homozygous dominant rat?

A homozygous organism has two copies of the same allele for a gene.

If an organism has two copies of the same dominant allele, it is homozygous dominant; if it has two copies of the same recessive gene, it is homozygous recessive.

What is the justification of the above answer?

Note that the total population of rats is: 200

Number of rats with brown fur = 112

The frequency of brown fur rats thus,

112/200

= 0.56

Note that it is also stated that the brown fur rats are dominant in relation to the gray fur rats. Thus, in accordance to Hardy Weinberg's equation, the frequency of the dominant rats is depicted as: p²

Thus:

p²  + 2pq = 0.56

Hence, the frequency of the the Homozygous recessive gray rats is given as:

p² + q² + 2pq = 1

q²  = 1 - 0.56

q² = 0.44

q = 0.663

P = 1-q

= 1 - 0.663

= 0.337

Thus the frequency of the homozygous dominant rats is:

= 0.337²

= 0.1135

≈ 0.11

Therefore the correct answer is A.

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A student is conducting their science experiment on the effect of caffeine on dogs. He has 3 groups of test subjects.
The 1st group of dogs receives plain water. The 2nd group of dogs receives 10 mg of caffeine each, and the 3rd
group receives 50 mg of caffeine each. He will measure their activity levels by recording how long each dog runs
without stopping, after giving them the pills. What could be evaluated in this experiment to ensure reliability?
A. If the dogs are different breeds, their activity levels could be different because of their breed and not the caffeine.
• B. The test subjects are dogs and not people, so their data is unreliable.
C. The different amounts of caffeine given could lead to different activity levels which would throw off the result of the experiment.
C D. The group that receives water will be an outlier and throw off the best fit line.

Answers

If the dogs are different breeds, their activity levels could be different because of their breed and not the caffeine. The correct option is A.

Reliability of experiments

In order for the outcomes of scientific experiments to be reliable, constant variables should be kept constant.

In the illustrated experiments, the breed and age of the experimental dogs have to be the same. It is one of the variables that have to be kept constant throughout the experiment.

If the dogs are different breeds, their activity levels could be different because of their breed and not the caffeine. The same thing is applicable to different ages.

Thus, evaluating this variable and doing right by it will ensure reliability.

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Which season is the Southern Hemisphere experiencing in the picture?

Answers

Answer: Summer

Explanation: When the southern hemisphere is closest to the sun, and it receives the most sunlight it is summer time, while in the northern hemisphere it's winter.

The main factor that determines seasons is the way sun rays enter Earth, and not as much proximity, since there is only a 2% variation in the distance overall

Select the possible energy sources for muscle contraction from the list.


•actin myofilaments
•blood glucose
• muscle glycogen
•glucagon

Answers

The possible energy sources for muscle contraction from the list include:

Blood glucoseMuscle glycogen.

What is Energy?

This is referred to as the ability to do work and the major fuel in the body is referred to as glucose.

Glycogen in muscles also acts as a fuel although its synthesis is usually very slow.

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What have you learned about the burying beetle and other insects that make them important to “The Natural World”?

Answers

Answer: Burying beetles are true to their name—they bury the carcasses of small vertebrates such as birds and rodents as a food source for their larvae.

Explanation:

they are on the endangered species list

jane goodall said that they are "nature's most efficient recyclers."

The American burying beetle is one of nature's most efficient recyclers, feeding and sheltering its own brood while returning nutrients to the earth to nourish vegetation and keeping ant and fly populations in check.

populations of prairie chickens and passenger pigeons have been reduced by the loss of the burying beetle.

biologicaldiversityorg

quizlet

Which organelle is responsible for producing the energy for cellular processes?
organelle A
organelle E
organelle F
organelle G

Answers

Organelle G which is the mitochondrion is responsible for producing the energy for cellular processes.

What is Mitochondrion?

This is referred to as the power house of the cell as it is the area where ATP(energy) is produced.

The energy is produced through aerobic respiration which is then used for various forms of activities by the cells.

The complete question is:

Consider this animal cell mc 006 - 1. jpg. Which organelle is responsible for producing the energy for cellular processes?

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Greenhouse gases

a) keep earth cool
B)absorb heat From the sun
C) Are only produced naturally
d) Trap Ozone At earths surface

Answers

Answer:

greenhouse gases produce or a heat from the sun bringing about global warming

B) absorb heat from the sun

Explanation:
When the suns UV rays hit the earth they get absorbed by the earths surface and then remitted as infrared light. This infrared light then gets absorbed and trapped here on earth by greenhouse gasses. If we did not have any greenhouse gasses the earth would be about -18°C

A sample of the element boron will have some atoms with six neutrons and some atoms with five neutrons; collectively, these atoms are called
OA. cations.
OB. anions.
OC. isotopes
OD. ions

Answers

Answer: OC. Isotopes

Explanation: Isotopes of element are those who have same numbr of protons but different number of neutrons. Here number of neutrons are different so these atoms are isotopes.

Classify the following organisms as eubacteria,archebacteria, Protists,fungi or other

Answers

Eubacteria and archaebacteria are organisms from the Archaea domain, whereas protists and Fungi belong to the Eukarya domain.

What are prokaryotic organisms?

Prokaryotic organisms such as eubacteria (E coli) and archaebacteria (methanogens) are unicellular microorganisms whose cells do not have a cell nucleus.

Conversely, eukaryotic cells such as protists (giardia lamblia) and fungi (Yeast) have the genetic material inside the cell nuclei and membrane-bound organelles.

In conclusion, eubacteria and archaebacteria belong to Archaea, whereas protists and Fungi belong to Eukarya.

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Two fully heterozygous fruit flies are crossed. Complete the Punnett square and provide the probabilities for the genotype and phenotype for the offspring.
B= brown body
b= black body
E= red eyes
e= brown eyes
Please provide the probability in percentages
Fill in the blanks using the show your work tools

Answers

Answer:

Blanks in the boxes (left to right, top to bottom, as you would read)

BbEE
BbEE

BbEe

bbee

Genotypes (top to bottom blanks):

12.5%

6.25%

6.25%

Phenotype (top to bottom blanks):

56.25%

18.75%

18.75%

The cichlid is a colorful fish found in freshwater lakes. There are over a thousand species of cichlid fish today. If a species of cichlid became extinct, the niche the fish filled within the ecosystem would be left open. Explain how an available niche after extinction can lead to speciation.

Answers

An available niche after extinction can lead to speciation because it allows the emergence of genetic variation in other competing species.

What is speciation?

Speciation is a slow process associated with the emergence of reproductive isolation barriers in a population.

These barriers lead to the absence of gene flow and eventually to the emergence of new species.

In conclusion, an available niche can lead to speciation in other competing species.

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While most other organisms obtain energy from food, plants get their energy from the sun. Would you support research to genetically modify humans to be able to use photosynthesis for part of our energy and reduce the amount of food we need?

I need 3-5 sentence answer.

Answers

No, I won't support research to genetically modify humans to be able to use photosynthesis for part of our energy and reduce the amount of food we need.

What is Photosynthesis?

This is the process in which green plants manufacture their food in the presence of sunlight.

The research won't be supported as a result of the absence of the digestive system to suit the product and reducing amount of food needed will lead to wastage.

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A proton gradient is an important part of both photosynthesis and cellular respiration.

For either photosynthesis or cellular respiration, describe how the proton gradient is established and what the proton gradient is used for.

Answers

A proton gradient is an important part of both photosynthesis and cellular respiration because couple the favorable flow of H+ to transport specific metabolites into and out of organelles.

What is the proton gradient?

The gradient is sometimes called the proton-motive and can be thought of as a form of energy, force and force in a battery. Like other ions, protons are not able to cross directly through the phospholipid bilayer of the membrane, as the interior of the membrane is hydrophobic.

The proton gradient generated by this manipulation provided a driving force for ATP synthesis in the absence of light. This confirms the chemiosmotic theory, where a chemical potential across the membrane can provide energy for ATP synthesis.

The proton gradient produced by pumping protons during the electron transport chain is used to synthesize ATP.

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Reactions where an electron (or hydrogen) pass from one atom or molecule to another are called:

Question 18 options:

enzyme mediated


energy capturing


fermentation


oxidation-reductions

Answers

Reactions, where an electron (or hydrogen) passes from one atom or molecule to another, are called oxidation-reductions

A chemical reaction known as an oxidation-reduction (redox) reaction includes the exchange of electrons between two substances. Any chemical reaction in which the oxidation number of a molecule, atom, or ion changes by acquiring or losing an electron is referred to as an oxidation-reduction reaction.

Oxidation reaction: An oxidation reaction is a chemical reaction in which oxygen is acquired or hydrogen is destroyed. such as the 2Cu+O2heating 2CuO Reduction response. Reduction reactions occur when either hydrogen or oxygen is acquired or lost. such as CuO+H2heating Cu+H2O

When a reactant loses electrons in a reaction, oxidation takes place. When a reactant obtains electrons during a reaction, reduction takes place. This frequently happens when acid and metals react.

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3. What does the name protozoa mean?
first organism
first animal
first cell
first microbe

Answers

a group of single-celled eukaryotes.
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